MIF (macrophage migration inhibitory factor (glycosylation-inhibiting factor))
نویسندگان
چکیده
منابع مشابه
Correlation between urine macrophage migration inhibitory factor (MIF)/creatinine ratio and time after kidney transplantation
Abstract Background: Despite the long-standing association of macrophage migration inhibitory factor (MIF) with delayed-type hypersensitivity response, the potential role of MIF in chronic allograft nephropathy is unknown. The association between upregulation of MIF expression, macrophage and T cell infiltration and the severity of chronic allograft nephropathy suggests that MIF may be an ...
متن کاملMacrophage migration inhibitory factor (MIF), a role in COPD
Authors: 5 Gunnar R. Husebø, Per S. Bakke, Rune Grønseth, Jon A. Hardie, Thor Ueland, Pål 6 Aukrust, Tomas M.L. Eagan. 7 8 Dept. of Thoracic Medicine, Haukeland University Hospital, Bergen Norway 9 2 Dept. of Clinical Science, University of Bergen, Norway 10 Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway 11 K.G. Jebsen Inflammatory Research Centre...
متن کاملCurrent developments of macrophage migration inhibitory factor (MIF) inhibitors.
The cytokine macrophage migration inhibitory factor (MIF) is regarded as a major regulator of inflammation and a key mediator that counter-regulates the inhibitory effects of glucocorticoids within the immune system. Therefore, MIF is a therapeutic target for the treatment of inflammatory and autoimmune diseases. In addition, MIF was found to be implicated in cancer pathogenesis. Current therap...
متن کاملMacrophage migration inhibitory factor (MIF) enzymatic activity and lung cancer.
The cytokine macrophage migration inhibitory factor (MIF) possesses unique tautomerase enzymatic activity, which contributes to the biological functional activity of MIF. In this study, we investigated the effects of blocking the hydrophobic active site of the tautomerase activity of MIF in the pathogenesis of lung cancer. To address this, we initially established a Lewis lung carcinoma (LLC) m...
متن کاملHuman Macrophage Migration Inhibitory Factor (mif): a Proven Immunomodulatory Cytokine?
HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF): A PROVEN IMMUNOMODULATORY CYTOKINE? Alex Kudrin‡, Martin Scott§, Steven Martin§, Chun-wa Chung§, Rachelle Donn¶¥, Andrew McMaster¥, Stuart Ellison¥, David Ray¶, Keith Ray‡, Michael Binks‡ From the ‡Department of Disease Biology, Rheumatology and Inflammation, GlaxoSmithKline, Stevenage, United Kingdom, SG1 2NY. §Discovery Research, GlaxoSmithK...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/44983